Cell-Type-Resolved Placental Epigenomics Identifies Clinically Distinct Subtypes of Preeclampsia Yuheng Du, Ph.D. Student, Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA; Paula A. Benny, Research Scientist, Department of Obstetrics and Gynecology, University of Hawaii, Honolulu, HI, USA; Fadhl M. AlAkwaa, Assistant Research Scientist, Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Cameron B. Lassite

Interpretable Multimodal Interaction-aware Mixture-of-Experts Jiayi Xin, BS, PhD Student, University of Pennsylvania, PA, USA Sukwon Yun, MS, PhD Student, University of North Carolina at Chapel Hill, NC, USA Jie Peng, BS, PhD Student, University of Science and Technology of China, Anhui, China Inyoung Choi, BS, PhD Student, University of Pennsylvania, PA, USA Jenna L. Ballard, BS, PhD Student, University of Pennsylvania, PA, USA Tianlong Chen, PhD, University o

Tumor subtype and clinical factors mediate the impact of tumor PPARɣ expression on outcomes in patients with primary breast cancer. Aditya Shah1,2, Katie Liu1,3, Ryan Liu1, 4, Gautham Ramshankar1, Curtis J. Perry MD, Ph.D.5,6, and Rachel J. Perry Ph.D1* 1Departments of Cellular & Molecular Physiology, Internal Medicine (Endocrinology), and Comparative Medicine, Yale University, New Haven, CT, United States 2Woodbridge Academy Magnet School, Woodbridge, NJ, United States

Single Cell Analysis based Identification of Unique Markers and Metastasis Mechanism in Triple Negative Breast Cancer Aashi Dixit Triple-negative breast cancer (TNBC) is a subtype of breast cancer which has none of the known unique biomarkers of the other subtypes. There is no established targeted treatment for TNBC and rare early diagnosis, which is also metastatic in 46% of cases, leading to poor survival rates in patients. Single-cell analysis maps the genomic information

KnowYourCG: Enabling CpG-centric Interpretation of Sparse DNA Methylomes Hongxiang Fu1,* David C Goldberg1,* Daniel Atkins1, Ethan Moyer1, Chin Nien Lee2, Yanxiang Deng2, Wanding Zhou1 1Center for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, PA, 19104, USA, 2Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA *Authors contributed equally. Decoding DNA methylomes for biological insights i