Refined Characterization of Circulating Tumor DNA Through Biological Feature Integration

Havell Markus†&, Dineika Chandrananda&, Elizabeth Moore, Florent Mouliere*, James Morris, James Brenton, Christopher G. Smith#, and Nitzan Rosenfeldj#

1.Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

2.Cancer Research UK Major Centre – Cambridge, Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.

*Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Cancer Centre Amsterdam, 1081 HV, Amsterdam, The Netherlands.

†Pennsylvania State College of Medicine, 700 HMC Cres Rd, Hershey, PA 17033

&These authors contributed equally to this work

j#These authors jointly supervised this work

Submitting Author: Havell Markus

Contact: hmarkus@pennstatehealth.psu.edu or nitzan.rosenfeld@cruk.cam.ac.uk