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MELTRON: Detecting Large Scale Chromatinde Condensation Events from 3D Contact Maps

Updated: Oct 26

Dominik Szabó(1,2,#), Warren Winick-Ng(1,#,*), Alexander Kukalev(1,#), Izabela Harabula(1,2,#), Luna Zea Redondo(1,2,#), Mandy Meijer(3), Leonid Serebreni1, Simona Bianco(4), Andrea M. Chiariello(4), Ibai Irastorza-Azcarate1,Christoph J.Thieme(1), Thomas M. Sparks(1,2), Sílvia Carvalho(1,5,6,7), Luca Fiorillo(4), Francesco Musella(4), Ehsan Irani(1,8),Elena Torlai Triglia(1), Aleksandra A. Kolodziejczyk(9,10), Andreas Abentung(11,d), Galina Apostolova(12), Eleanor J. Paul(12), Vedran Franke(13), Rieke Kempfer(1,2), Altuna Akalin(13), Sarah A. Teichmann(9,10), Georg Dechant(11), Mark A. Ungless(12), Mario Nicodemi(4,8), Gonçalo Castelo-Branco(3,14), Ana Pombo(1,2,8,*)

1.Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine,Berlin, Germany; 2.Humboldt-Universität zu Berlin, Berlin, Germany; 3.Laboratory of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden; 4.Dipartimentio di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso Universitario di Monte Sant'Angelo, Naples, Italy; 5.UCIBIO, Department of Life Sciences, NOVA School of Science and Technology, Universidade NOVA de Lisboa, Caparica, Portugal; 6.Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal; 7.Graduate Program in Areas of Basic and Applied Biology, Universidade do Porto, Porto, Portugal; 8.Berlin Institute of Health, Berlin, Germany; 9.Cavendish Laboratory, University of Cambridge, JJ Thomson Ave, Cambridge, UK; 10.Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK; 11.Institute for Neuroscience, Medical University of Innsbruck, Innsbruck, Austria; 12.Institute of Clinical Sciences, Imperial College London, London, UK; 13.Bioinformatics and Omics Data Science Platform, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Berlin, Germany; 14.Ming Wai Lau Centre for Reparative Medicine, Stockholm node, Karolinska Institutet, Stockholm, Sweden. #These authors contributed equally to this work. *Corresponding authors


Submitting Author: Dominik Szabo


Contact: dominik.szabo@mdc-berlin.de








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