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Jiyang Yu, PhD


Associate Member, St. Jude Faculty

Interim Chair, Department of Computational Biology

St Jude Children's Research Hospital


Dr. Yu's research is focused on developing data-driven systems biology algorithms to integrate bulk, single-cell, and spatial omics data to decipher these (re)wiring events and hidden drivers underpinning biological processes in health and disease. Ultimately, we aim to translate the hidden driver discoveries into therapeutic targets, biomarkers, and combination therapies for cancer and other disorders.


He earned his undergraduate degree in Computer Science from Zhejiang University, China in 2006. He trained in Dr. Andrea Califano’s laboratory at Columbia University 2008–2012 and earned his PhD degree in Biomedical Informatics. His studies were focused on integrating functional genomics with systems biology to discover drivers and therapeutic targets of human malignancies. After his PhD training, Dr. Yu joined Pfizer Oncology as a senior scientist to work on cancer precision medicine. In November 2016, Dr. Yu joined St. Jude as faculty in the Department of Computational Biology where he continues to pursue his passion for perfecting translational systems biology approaches to developing cancer treatment.

(Source: St. Jude Children's Research Hospital)

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